פרקים נבחרים בביולוגיה של הסרטן (0421.3811)

שם הקורס באנגלית: Selected Chapters in Cancer Biology

מספר קורס סמסטר יום משעה עד שעה בניין חדר
0421.3811.01 ב ב 14:00 16:00 בריטניה 005

 

סילבוס:

 
  • Introduction – The Hallmarks of Cancer (Dino – 1 lesson)
  • Tumor immunology and Immunotherapy (Adit – 2 lessons)
    • Tumor infiltrating lymphocytes (TILs, TILs in cancer therapy)
    • Immune checkpoints
    • Engineered T cells
  • Tumor microenvironment (TME) (Lior – 3 lessons)
    • Players of the TME - Stroma cells
    • Reprogramming of the TME
    • Metabolic Interactions in the Tumor Microenvironment
    • Dissecting the Tumor Microenvironment
  • Glycoimmunology of Cancer (Vered – 2 lessons)
    • Carbohydrates in tumor initiation, progression and metastasis
    • Glycan receptors in tumor initiation, progression and metastasis
    • Involvement of glycans in the hallmarks of cancer
    • Novel approaches for glycotherapy of cancer
  • Stem cells and Tumor Heterogeneity (Dino – 1 lesson)
    • Stem cells/Cancer Stem Cell
    • Tumor plasticity
    • Tumor heterogeneity (spatial, temporal, intra and inter-heterogeneity)
  • Mouse models of Cancer (Dino – 1 lesson)
    • Mutagenic induced models
    • Allograft/Xenograft models
    • Transgenic/Knockout models
    • Viral induced models
  • Tumor Angiogenesis (Dino – 1 lesson)
    • Normal and neoplastic endothelial cells
    • Angiogenic switch
    • Anti-angiogenic therapies
  • Cancer Therapeutics (Dany – 2 lessons)
    • Chemotherapy
    • Protein therapy
    • Radiotherapy
    • Targeted therapy
    • Drug delivery systems

           

 
דרישות קדם:  Cell biology, Molecular biology and biotechnology, Genetics.
 
נוכחות חובה
 
מטלת סיום: ​ multiple choice (American style)
 
הרכב ציון: 
 
אוניברסיטת תל-אביב, ת.ד. 39040, תל-אביב 6997801
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